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ACRIA Update
Winter 2008 - Vol.17 No. 1

ACRIA NEWS

ACRIA at USCA
ACRIA played a prominent role in last year’s United States Conference on AIDS, held in Palm Springs, California, in November 2007.

Associate Director for Research Stephen Karpiak, Ph.D., who was co-principal investigator of ACRIA’s groundbreaking Research on Older Adults with HIV (ROAH) study, chaired and spoke at a roundtable presentation on “The Graying of HIV.”  Other participants in the discussion were ACRIA Executive Director Daniel Tietz and consultant J. Edward Shaw.

We also had our first-ever USCA exhibit booth, staffed by HIV Health Literacy Program Administrative Coordinator Gustavo Otto.  Conference attendees who visited our booth were able to learn a lot about ACRIA’s work and were given a CD that contained a large sampling of educational materials and a complete copy of the ROAH report. 

A broad range of the HIV Health Literacy Program’s educational materials was displayed, including several issues of ACRIA Update and copies of all five of our existing educational publications—all in both English and Spanish versions—along with order forms.  Of special interest was information about our newest booklet, the soon-to-be-published Older Adults and HIV, which generated a large number of prepublication orders.

Welcome, Robert!
ACRIA is pleased to welcome Robert Burke, founder and principal of the leading New York City luxury consulting business Robert Burke Associates, to our Board of Directors.  Before founding RBA in early 2006, Burke spent eleven years at Ralph Lauren, overseeing that company’s fashion operations in the U.S. and abroad, and in 1999 moved on to become senior vice president of fashion and public relations at Bergdorf Goodman.

Congratulations, Martha!
At its April meeting, ACRIA’s Board of Directors elected Martha Nelson as its president, and she was welcomed to her new post at a special reception held on November 19.  Over fifty Board members, donors, and friends of ACRIA attended this event, held at Donna Karan’s Urban Zen boutique.

A recognized leader in the magazine industry, as Group Editor at Time, Inc., Ms. Nelson supervises five titles, including People and InStyle magazines.  She has been an ACRIA supporter since 1997 and a Board member nearly that long.  She succeeds long-time ACRIA Board president Ross Bleckner.

Dinner Benefits ACRIA
ACRIA’s Twelfth Annual Holiday Dinner benefit, held on December 11, raised a record-breaking $300,000-plus to support our vital research and health literacy services for people with HIV and those at risk.

Over 200 guests joined ACRIA in honoring National Advisory Council member Bob Colacello for his longstanding support for ACRIA and his deep commitment to the fight against HIV/AIDS.  Donna Karan once again hosted this very special evening at her Stephan Weiss Studio, along with co-hosts Ross Bleckner, Reinaldo and Carolina Herrera, Charla Lawhon, and Martha Nelson.  Grammy-nominated singer/songwriter Vanessa Carlton was on hand for a special performance.  Special thanks for the success of the evening go to supporters InStyle magazine; Paul Beirne; Urban Zen; Altria; Andre Balazs Properties; HL Group; John Hardy, Ltd.; and Calvin Klein, Inc.

Thank You, Partners
ACRIA’s HIV Health Literacy Program wants to thank staff of our partner agencies that have provided sites for our staff and client workshops:  Denise Mauro of the Salvation Army; Janice Sinkler of the Jamaica Hospital Medical Centers; Patrick Dolby of Housing Works in Brooklyn and Robin Lutz of Housing Works in Manhattan; Cesar Barreto of Hostos Community College; Carlene Numa of FACES; and Lorena Flores of Steinway Child and Family Services.

Artists’ Foundations Support ACRIA Study
ACRIA’s ongoing research into issues important to people with HIV over the age of 50 has gained support from the estates of two prominent artists lost to AIDS.  The Robert Mapplethorpe Foundation and the Keith Haring Foundation have each contributed $50,000 to ACRIA to conduct a study aimed at demonstrating that depression can be rapidly identified and given sustained treatment in a high-risk population of HIV-positive people over 50.

Robert Mapplethorpe was a photographer whose black-and-white images ranged from flowers and portraits of famous people to explicitly homoerotic and sadomasochistic themes.  It was the latter that made him a lightning rod for controversy, particularly in frequently acrimonious debates over public funding for the arts.  Keith Haring’s subway-style art and “radiant” images are instantly recognizable and often imitated.

Both artists died of AIDS-related illnesses during what was perhaps the darkest period of the epidemic, Mapplethorpe in 1989 and Haring in 1990. As Julia Gruen, Executive Director of the Keith Haring Foundation noted in her letter notifying ACRIA of the award:  “Had they been fortunate enough to survive, both Keith and Robert would have been among the older adults living with HIV targeted by the study.  The Board felt it appropriate that the generosity and foresight of these two artists would benefit their peers who survived them.”

The study, which is already under way, is being led by ACRIA’s Associate Director for Research Stephen Karpiak, Ph.D., and Senior Research Scientist Mark Brennan, Ph.D.  It is being conducted in cooperation with Harlem United.


ACRIA Trials in Progress

Crofelemer for Diarrhea
People 18 and older who have persistent diarrhea will first take crofelemer or placebo tablets for 6 weeks.  Then everyone will take crofelemer for 5 months.

Avandia and Serostim
People with insulin resistance will take Avandia (rosiglitazone), or Serostim (growth hormone),  or both for 6 months to see how they affect glucose, insulin levels and body shape.

KP-1461
People aged 18-60 who have taken an NRTI, NNRTI and PI, and have developed resistance or stopped the drugs for other reasons, will take KP-1461 (a new type of NRTI) with no other ARVs for four months.

SPRING: Aptivus in Diverse Populations
People 18 and older (half white and half non-white, half men and half women) who have taken an NRTI, NNRTI and PI (not Aptivus) and who have resistance to at least two PIs, will take a standard dose of Aptivus or receive therapeutic drug monitoring to find the best dose for them.

IMPACT: Reyataz Resistance
People who have developed resistance to Reyataz will come in for one day of blood tests to study the I50L mutation.

CHAMPS
People aged 18 and over who have resistance to at least three classes of HIV meds will take either maraviroc (Selzentry) or INCB 9471, a new once-per-day CCR5 inhibitor.

Ibalizumab
In addition to oral HIV meds, people will be given IV infusions of placebo or one of four doses of ibalizumab, a monoclonal antibody designed to block HIV entry.

Prezista Dosing
People 18 and older who have been taking HIV meds for at least 12 weeks will take Prezista with Norvir either once a day or twice a day, along with other HIV meds.

For more information on these trials, contact us at 212-924-3934 ext. 121.


Etravirine (TMC 125) Expanded Access (closed to enrollment)
People 18 and older who have limited treatment options and resistance to approved NNRTIs, and who have taken an NRTI, NNRTI and at least two PIs, may qualify for early access to this experimental NNRTI. 

Transacin (NGX-4010) (closed to enrollment)
People with HIV who have peripheral neuropathy will use either Transacin (capsaicin) patches or very low-dose patches for 30 or 60 minutes a day for 3 months.  Participants must be 18 or older and have had pain in both feet for at least 2 months.

TH9507 (closed to enrollment)
People aged 18-65 who have excess abdominal fat will take either TH9507 (an investigational growth hormone releasing factor), or a placebo for 26 weeks.  The two groups will then switch for 26 more weeks.



GENEROUS CONTRIBUTIONS

The following persons, corporations and organizations made major donations between October 1 and December 31, 2007 to support ACRIA's research and education efforts:

Albert Einstein College of Medicine
Altria
Calvin Klein, Inc.
The Elton John AIDS Foundation
Gilman Family Foundation
In Style Magazine
John Hardy, Ltd.
Just Give
The MAC AIDS Fund
New York State Dept. of Health AIDS Institute
Stavros S. Niarchos Foundation
The Shana Alexander Charitable Foundation
The Diller-Von Furstenberg Family  Foundation
Jeff Altman
Donald Baechler
Andre Balazs
Dr. Christopher B. Barley  and Jonathan Sheffer
Paul Beirne
Cheryl Berger
James Best
Zach Buchwald
Robert Burke
Russell Calabrese
Jose M. Castro
Olivia Chantecaille
Donald Christiansen
Adriana Cisneros
Bob and Suzanne Cochran
Bob Colacello
Dr. Yael Danieli
Ernie De La Torre
Scott Drevnig
Tiffany Dubin
Patricia Duff
Abraham Dweck
Luis Valverde Espejo
Kenny Felberbaum
Vincent and Shelly Fremont
Jill Friedson
Sandy Gallin
Jon Gilman and Brad Learmonth
Dr. Kay E. Goldberg
Santiago Barberi Gonzalez
Dave Greenblatt
John Gregory
Scott Grover


Agnes Gund and Daniel Shapiro
Geoffrey Handler
Gillian Hearst-Shaw
John B. Hess
Caroline Hirsch
Stephen Holden-Style
Andreas Hommert
Thomas Hudson
Marianne Hyde
Michelle Isaacson
Jay Johnson and Tom Cashin
Chris Kann
David Kleinberg
George Kolasa
Tim Lammers
Adam F. Lippes
Joseph Little
Julie Macklowe
Angela Mariani
Eric Menkes
Nicole Miller
Mark Montgomery and Stephen Kinsella
Susan Morris
Wayne Nathan
Martha Nelson
Stuart Parr
Greg Paulneck
Tatiana Platt
Kammi Reiss
Timothy Rhodes
David Salle
Barry and Sheryl Schwartz
Steven Sclaroff
Nathan Serphos
Sam Shahid
Dr. and Mrs. John Sherman
Jill Simon
Wendy Smith
David Stark
Peter R. Stern
Todd Strum
Richard S. Swenson
Mr. and Mrs. Elie Tahari
Maggie Talisman
Dr. Pritinder K. Thind
Antony Todd
Timothy Whealon
Terry Wilfong
                                                                 


ACRIA UPDATE ACRIA Board of Directors In Memorium
Editor in Chief
Daniel Tietz

Editors
Mark Milano
Luis Scaccabarrozzi

Medical Editor
Jerome A. Ernst, MD

Publications Manager Mark Milano

Pulblications Associate Laura Engle

Martha Nelson, President
Donald Kotler, MD, Vice President
Charles Franchino, DC, Secretary
Mark Montgomery, Treasurer
Ross Bleckner
Robert Burke

Marisa Cardinale
Francisco Costa
Alphonso David
Vincent Wm. Gagliostro
Deborah Hughes
Leslie Koltz
Christopher Murray
Judith Rabkin, PhD. MPH
Isabel Rattazzi
Vaughn Williams
Barry Binkowitz, MD
Gary Bonasorte
Kiki Mason
David Seidner
George N. Stathakis

 
Executive Director
Daniel Tietz
Medical Director
Jerome A. Ernst, MD
ACRIA is an independent, non-profit, community-based AIDS medical research and treatment education organization dedicated to rapidly improving the length and quality of life for people living with HIV/AIDS. Bulk copies of ACRIA Update are available free to agencies that provide services to people living with HIV/AIDS. For more information, call 212-924-3934 ext. 129.

Copyright © 2008
AIDS Community Research Initiative of America.
All rights reserved. Non-commercial reproduction is encouraged provided appropriate credit is given.

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Phone: (212) 924-3934
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Internet address: www.acria.org 
                                                                 


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